Tumor-associated macrophages: unwitting accomplices in breast cancer malignancy
نویسندگان
چکیده
منابع مشابه
Flowcytometric Analysis of Tumor Associated Macrophages in Invasive Ductal Carcinoma of Breast
Background: Invasive ductal carcinoma is the most common type of breast cancer in Iran. Impaired immune responses occur frequently in cancer patients, but the mechanisms of the induced immune defects remain poorly understood. It is believed that infiltrated immune cells, especially macrophages, may provide help for tumor cell growth and metastasis. Objective: To analyze the status of tumor as...
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The development of a supportive vasculature is essential for tumor progression. In a mouse model of breast cancer, we found that tumor-associated macrophages that are recruited to the tumor just before malignant conversion are essential for the angiogenic switch. These findings establish a causal linkage to explain well-documented clinical correlations between macrophages, microvessel density, ...
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ژورنال
عنوان ژورنال: npj Breast Cancer
سال: 2016
ISSN: 2374-4677
DOI: 10.1038/npjbcancer.2015.25